The risk of hyperplasia or endometrial cancer is
effectively counteracted by the association of estrogen with progesterone (Albright,
2000).
At per menopause, on average up to 4 years before
the full stop menses, the patient usually seeks the doctor complaining of
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The primary goal of therapy in these patients is the
restoration of menstrual regularity.
In these cases, the use of cyclic progestin is the
most appropriate treatment
Hormone
Replacement Therapy (HRT) is the conventional administration of estrogens
alone, and so indeed it is a Estrogen Replacement Therapy (ERT).
This TRE is
only used in women hysterectomy (no uterus) or associated with progestins, when
you want to protect the endometrial. A Hormone
Replacement Therapy (HRT) combined can be used
cyclically or continuously.
In a cyclical estrogen is administered continuously
for 21 days or monthly, whereas progesterone is administered only during 10 to
14 days.
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The
suspension of progesterone normally cause menstrual bleeding, therefore, is a
preferred scheme premenopausal or in early post menopause.
On a continuous combined HRT patient to receive
associated with daily estrogen and progestin, developing endometrial atrophy
and therefore no monthly withdrawal bleeding. This is the preferred form of HRT
in postmenopausal women later. Another option for the treatment of
postmenopausal women is tibolone (which is a synthetic steroid that is not
estrogen or progesterone but nevertheless properties estrogenic and androgenic.
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